| Identification | Back Directory | [Name]
2-Phenanthrenecarboxamide, 6-cyano-4b,7,8,8a,9,10-hexahydro-3-methoxy-4b,8,8-trimethyl-7-oxo-N-[3-(trifluoromethoxy)phenyl]-, (4bS)- | [CAS]
2125724-38-9 | [Synonyms]
2-Phenanthrenecarboxamide, 6-cyano-4b,7,8,8a,9,10-hexahydro-3-methoxy-4b,8,8-trimethyl-7-oxo-N-[3-(trifluoromethoxy)phenyl]-, (4bS)- | [Molecular Formula]
C27H25F3N2O4 | [MOL File]
2125724-38-9.mol | [Molecular Weight]
498.49 |
| Hazard Information | Back Directory | [Uses]
SH498, a novel Bmi-1-mediated antitumor agent, shows potent antiproliferative activity. | [References]
[1] Yang LF, et al. Synthesis of Cyanoenone-Modified Diterpenoid Analogs as Novel Bmi-1-Mediated Antitumor Agents. ACS Med Chem Lett. 2018 Sep 27;9(11):1105-1110. DOI:10.1021/acsmedchemlett.8b00345 |
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