| Identification | Back Directory | [Name]
Carbamic acid, N-[(1S)-1-[[4-(1-naphthalenylcarbonyl)-1-piperazinyl]carbonyl]-5-[(1-oxo-2-propen-1-yl)amino]pentyl]-, phenylmethyl ester | [CAS]
2134114-20-6 | [Synonyms]
Carbamic acid, N-[(1S)-1-[[4-(1-naphthalenylcarbonyl)-1-piperazinyl]carbonyl]-5-[(1-oxo-2-propen-1-yl)amino]pentyl]-, phenylmethyl ester | [Molecular Formula]
C32H36N4O5 | [MOL File]
2134114-20-6.mol | [Molecular Weight]
556.65 |
| Hazard Information | Back Directory | [Description]
AA9 is a novel transglutaminase (TG2) inhibitor. | [Uses]
AA9 is a potent Transglutaminase 2 (TG2) inhibitor. AA9 strongly impacts HIF-mediated hypoxia in MDA-MB-231 cells[1]. | [References]
[1] Ancona P, et al. Transcriptomics Studies Reveal Functions of Transglutaminase 2 in Breast Cancer Cells Using Membrane Permeable and Impermeable Inhibitors. J Mol Biol. 2024 May 15;436(10):168569. DOI:10.1016/j.jmb.2024.168569 |
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