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2135309-56-5

2135309-56-5 Structure

2135309-56-5 Structure
IdentificationBack Directory
[Name]

2-Imidazolidinone, 5-(1-methylethyl)-1-[2-[[(1S)-1-[1-[4-(trifluoromethyl)phenyl]-1H-imidazol-4-yl]ethyl]amino]-4-pyrimidinyl]-, (5S)-
[CAS]

2135309-56-5
[Synonyms]

IDH1 Inhibitor 7
2-Imidazolidinone, 5-(1-methylethyl)-1-[2-[[(1S)-1-[1-[4-(trifluoromethyl)phenyl]-1H-imidazol-4-yl]ethyl]amino]-4-pyrimidinyl]-, (5S)-
[Molecular Formula]

C22H24F3N7O
[MOL File]

2135309-56-5.mol
[Molecular Weight]

459.47
Chemical PropertiesBack Directory
[density ]

1.40±0.1 g/cm3(Predicted)
[form ]

Solid
[pka]

13.30±0.40(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

IDH1 Inhibitor 7 (Compound 88) is an IDH1 inhibitor with an IC50 of less than 100 nM[1].
[IC 50]

IDH1: <100 nM (IC50)
[References]

[1] Lei Jang, et al. Compound having mutant idh inhibitory activity, preparation method and use thereof. Patent WO2017162133A1.
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