| Identification | Back Directory | [Name]
1-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oic acid | [CAS]
2138440-78-3 | [Synonyms]
Pomalidomide-5'-PEG8-C2-COOH
1-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oic acid
Propanoic acid, 3-[[23-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-3,6,9,12,15,18,21-heptaoxatricos-1-yl]oxy]- | [Molecular Formula]
C32H47N3O14 | [MOL File]
2138440-78-3.mol | [Molecular Weight]
697.74 |
| Chemical Properties | Back Directory | [Boiling point ]
848.1±65.0 °C(Predicted) | [density ]
1.307±0.06 g/cm3(Predicted) | [form ]
Oil | [pka]
4.28±0.10(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
Pomalidomide-5'-PEG8-C2-COOH is an E3 Ligase Ligand-Linker Conjugates, consisting of Pomalidomide (HY-10984) and a linker. Pomalidomide-5'-PEG8-C2-COOH can be used for synthesis of PROTACs[1]. | [References]
[1] Posternak G, et al. Functional characterization of a PROTAC directed against BRAF mutant V600E. Nat Chem Biol. 2020 Nov;16(11):1170-1178. DOI:10.1038/s41589-020-0609-7 |
|
|