| Identification | Back Directory | [Name]
m-PEG2-Azide | [CAS]
215181-61-6 | [Synonyms]
mPEG2-N3
azido-mPEG2
m-PEG2-Azide
1-Azido-2-(2-methoxyethoxy)ethane
1-(2-Azidoethoxy)-2-methoxyethane
1-(1-ethoxy-2-azido)-2-methoxyethane
m-PEG2-Azide,m-PEG2-N3,1-(2-Azidoethoxy)-2-methoxyethane | [Molecular Formula]
C5H11N3O2 | [MDL Number]
MFCD19672689 | [MOL File]
215181-61-6.mol | [Molecular Weight]
145.16 |
| Hazard Information | Back Directory | [Description]
m-PEG2-azide is a PEG linker containing reactive azide group. The azide group is reactive with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. | [Uses]
m-PEG2-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG2-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | [References]
[1] Lepage ML, et al. Design, synthesis and photochemical properties of the first examples of iminosugar clustersbased on fluorescent cores. Beilstein J Org Chem. 2015 May 6;11:659-67. DOI:10.3762/bjoc.11.74 |
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Sigma-Aldrich
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