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2158265-96-2

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2158265-96-2 Structure

2158265-96-2 Structure
IdentificationBack Directory
[Name]

5H-Pyrazolo[4,3-c]pyridine-5-carboxamide, 3-[6-(difluoromethyl)-7-(1-methyl-1H-pyrazol-4-yl)-4-isoquinolinyl]-1,4,6,7-tetrahydro-N-methyl-1-(tetrahydro-2H-pyran-4-yl)-
[CAS]

2158265-96-2
[Synonyms]

CBP/p300-IN-2
CBP/EP300-IN-2
5H-Pyrazolo[4,3-c]pyridine-5-carboxamide, 3-[6-(difluoromethyl)-7-(1-methyl-1H-pyrazol-4-yl)-4-isoquinolinyl]-1,4,6,7-tetrahydro-N-methyl-1-(tetrahydro-2H-pyran-4-yl)-
[Molecular Formula]

C27H29F2N7O2
[MDL Number]

MFCD32215332
[MOL File]

2158265-96-2.mol
[Molecular Weight]

521.56
Chemical PropertiesBack Directory
[Boiling point ]

770.6±60.0 °C(Predicted)
[density ]

1.47±0.1 g/cm3(Predicted)
[pka]

14.12±0.20(Predicted)
Hazard InformationBack Directory
[Uses]

CBP/EP300-IN-2 is an inhibitor of CBP/EP300 with IC50 values of 1.07 nM and 5.96 nM for CBP/HTRF and Myc, respectively. CBP/EP300-IN-2, example 25, is extracted from patent WO2017205538A1[1].
[References]

[1] Patrick Cyr, et al. Pyrazolopyridine derivatives for the treatment of cancer
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