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2166487-21-2

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2166487-21-2 Structure

2166487-21-2 Structure
IdentificationBack Directory
[Name]

SIRT5 inhibitor
[CAS]

2166487-21-2
[Synonyms]

SIRT5 inhibitor
SIRT5 inhibitor 1
[Molecular Formula]

C31H39FN6O6S2
[MOL File]

2166487-21-2.mol
[Molecular Weight]

674.81
Chemical PropertiesBack Directory
[density ]

1.41±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO : 125 mg/mL (185.24 mM)
[form ]

Solid
[pka]

4.34±0.10(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

SIRT5 inhibitor 1 is a potent Human Sirtuin 5 deacylase inhibitor, with an IC50 of 0.11 μM.
[storage]

Store at -20°C
[References]

[1] Rajabi N, et al. Mechanism-Based Inhibitors of the Human Sirtuin 5 Deacylase: Structure-Activity Relationship, Biostructural, and Kinetic Insight. Angew Chem Int Ed Engl. 2017 Nov 20;56(47):14836-14841. DOI:10.1002/anie.201709050
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