ChemicalBook--->CAS DataBase List--->217099-44-0

217099-44-0

217099-44-0 Structure

217099-44-0 Structure
IdentificationBack Directory
[Name]

2-Thiophenecarboxylic acid 2-(aminoiminomethyl)benzo[b]thiophen-6-yl ester methanesulfonate (1:1)
[CAS]

217099-44-0
[Synonyms]

BCX 1470
BCX 1470;BCX-1470;BCX1470
BCX 1470 (Methanesulfonate)
2-(aminoiminomethyl)benzo[b]thiophen-6-yl ester 2-Thiophenecarbo
2-(aminoiminomethyl)benzo[b]thiophen-6-yl ester 2-Thiophenecarboxylic acid methanesulfonate
2-Thiophenecarboxylic acid 2-(aminoiminomethyl)benzo[b]thiophen-6-yl ester methanesulfonate (1:1)
2-Thiophenecarboxylic acid 2-(aminoiminomethyl)benzo[b]thiophen-6-yl ester methanesulfonate (1:1) ISO 9001:2015 REACH
[Molecular Formula]

C15H14N2O5S3
[MOL File]

217099-44-0.mol
[Molecular Weight]

398.47
Chemical PropertiesBack Directory
[storage temp. ]

Keep in dark place,Sealed in dry,2-8°C
[solubility ]

DMSO: ≥ 33.33 mg/mL (83.64 mM)
[form ]

Powder
[color ]

White to off-white
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
Hazard InformationBack Directory
[Uses]

BCX 1470 methanesulfonate inhibits the esterolytic activity of factor D (IC50=96 nM) and C1s (IC50=1.6 nM), 3.4- and 200-fold better, respectively, than that of trypsin.
[storage]

Store at -20°C
[References]

[1] Szalai AJ, et al. The Arthus reaction in rodents: species-specific requirement of complement.J Immunol. 2000 Jan 1;164(1):463-8. DOI:10.4049/jimmunol.164.1.463
[2] Szalai AJ, et al. The Arthus reaction in rodents: species-specific requirement of complement. J Immunol. 2000 Jan 1;164(1):463-8. DOI:10.4049/jimmunol.164.1.463
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