| Identification | Back Directory | [Name]
Serine, N-[[3-[(1E)-2-[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methylphenyl]ethenyl]-4-(trifluoromethyl)phenyl]methyl]-2-methyl- | [CAS]
2171558-14-6 | [Synonyms]
MAX-10181
PD-1/PD-L1-IN-30
Serine, N-[[3-[(1E)-2-[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methylphenyl]ethenyl]-4-(trifluoromethyl)phenyl]methyl]-2-methyl- | [Molecular Formula]
C29H28F3NO5 | [MOL File]
2171558-14-6.mol | [Molecular Weight]
527.53 |
| Chemical Properties | Back Directory | [Boiling point ]
664.6±55.0 °C(Predicted) | [density ]
1.318±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
2.15±0.15(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
MAX-10181 (PD-1/PD-L1-IN-30) is a PD-1/PD-L1 binding inhibitor, with an IC50 value of 0.018 μM. MAX-10181 can be used for research of cancers and other related diseases[1]. | [References]
[1] Wang, Yuguang, et al. Aromatic acetylene or aromatic ethylene compound, intermediate, preparation method, pharmaceutical composition and use thereof. Patent. WO2018006795. |
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