| Identification | Back Directory | [Name]
cMK801 | [CAS]
217176-91-5 | [Synonyms]
cMK801
Caged MK801
Caged MK801 >=98% (HPLC)
Caged MK 801, NMDA receptor open-channel blocker
Dizocilpine N-(4,5-dimethoxy-2-nitrobenzyl) carbamate
10,11-Dihydro-5-methyl-5H-dibenzo[a,d]cyclohepten-5,10-imine-12-carboxylic acid (4,5-dimethoxy-2-nitrophenyl)methyl ester
5H-Dibenzo[a,d]cyclohepten-5,10-imine-12-carboxylic acid, 10,11-dihydro-5-methyl-, (4,5-dimethoxy-2-nitrophenyl)methyl ester | [Molecular Formula]
C26H24N2O6 | [MOL File]
217176-91-5.mol | [Molecular Weight]
460.49 |
| Chemical Properties | Back Directory | [Boiling point ]
605.535±55.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.329±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [storage temp. ]
2-8°C | [solubility ]
DMSO: ≥10mg/mL | [form ]
powder | [pka]
-1.846±0.40(predicted) | [color ]
white to light yellow |
| Hazard Information | Back Directory | [Uses]
Caged MK801 (cMK801) is a selective, non-competitive, irreversible NMDA receptor open-channel blocker. NVOC cages are neuro pharmocologically compatible[1]. | [References]
[1] Antonio Rodríguez-Moreno, et al. Presynaptic induction and expression of timing-dependent long-term depression demonstrated by compartment-specific photorelease of a use-dependent NMDA receptor antagonist. J Neurosci. 2011 Jun 8;31(23):8564-8569. DOI:10.1523/JNEUROSCI.0274-11.2011 |
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| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
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