ChemicalBook--->CAS DataBase List--->217176-91-5

217176-91-5

217176-91-5 Structure

217176-91-5 Structure
IdentificationBack Directory
[Name]

cMK801
[CAS]

217176-91-5
[Synonyms]

cMK801
Caged MK801
Caged MK801 >=98% (HPLC)
Caged MK 801, NMDA receptor open-channel blocker
Dizocilpine N-(4,5-dimethoxy-2-nitrobenzyl) carbamate
10,11-Dihydro-5-methyl-5H-dibenzo[a,d]cyclohepten-5,10-imine-12-carboxylic acid (4,5-dimethoxy-2-nitrophenyl)methyl ester
5H-Dibenzo[a,d]cyclohepten-5,10-imine-12-carboxylic acid, 10,11-dihydro-5-methyl-, (4,5-dimethoxy-2-nitrophenyl)methyl ester
[Molecular Formula]

C26H24N2O6
[MOL File]

217176-91-5.mol
[Molecular Weight]

460.49
Chemical PropertiesBack Directory
[storage temp. ]

2-8°C
[solubility ]

DMSO: ≥10mg/mL
[form ]

powder
[color ]

white to light yellow
Safety DataBack Directory
[Hazard Codes ]

Xn
[Risk Statements ]

22
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

Caged MK801 (cMK801) is a selective, non-competitive, irreversible NMDA receptor open-channel blocker. NVOC cages are neuro pharmocologically compatible[1].
[References]

[1] Antonio Rodríguez-Moreno, et al. Presynaptic induction and expression of timing-dependent long-term depression demonstrated by compartment-specific photorelease of a use-dependent NMDA receptor antagonist. J Neurosci. 2011 Jun 8;31(23):8564-8569. DOI:10.1523/JNEUROSCI.0274-11.2011
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