| Chemical Properties | Back Directory | [Boiling point ]
909.7±65.0 °C(Predicted) | [density ]
1.276±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
Soluble in Water, DMSO, DMF, Methanol | [form ]
Solid | [pka]
4.28±0.10(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Description]
(S, R, S)-AHPC-PEG2-acid is a syntheticPROTAC linker molecule that incorporates an E3 ligase ligand with a PEG linker to empower PROTAC drug research & discovery. The hydrophilic PEG spacer increases the solubility of a compound in aqueous media. | [Uses]
(S,R,S)-AHPC-PEG2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [storage]
Store at -20°C | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
|
|