| Identification | Back Directory | [Name]
NH-bis(PEG2-Boc) | [CAS]
2182601-69-8 | [Synonyms]
NH-bis(PEG2-Boc)
NH-bis(C2-PEG2-NH-Boc)
5,8,14,17-Tetraoxa-2,11,20-triazaheneicosanedioic acid, 1,21-bis(1,1-dimethylethyl) ester | [Molecular Formula]
C22H45N3O8 | [MDL Number]
MFCD31536767 | [MOL File]
2182601-69-8.mol | [Molecular Weight]
479.61 |
| Chemical Properties | Back Directory | [Boiling point ]
577.0±50.0 °C(Predicted) | [density ]
1.064±0.06 g/cm3(Predicted) | [solubility ]
Soluble in Water, DMSO, DMF, DCM | [form ]
Liquid | [pka]
11.93±0.46(Predicted) | [color ]
Colorless to light yellow |
| Hazard Information | Back Directory | [Description]
NH-bis(PEG2-Boc) is a Boc protected amine molecule whiich is reactive with carboxylic acids, activated NHS esters,. Boc can be deprotected under acidic conditions. | [Uses]
NH-bis(C2-PEG2-NH-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs; Alkyl/ether | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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