| Identification | Back Directory | [Name]
NH-bis(PEG4-Boc) | [CAS]
2182601-75-6 | [Synonyms]
NH-bis(PEG4-Boc)
NH-bis(PEG4-C2-NH-Boc)
5,8,11,14,20,23,26,29-Octaoxa-2,17,32-triazatritriacontanedioic acid, 1,33-bis(1,1-dimethylethyl) ester | [Molecular Formula]
C30H61N3O12 | [MDL Number]
MFCD31536762 | [MOL File]
2182601-75-6.mol | [Molecular Weight]
655.82 |
| Hazard Information | Back Directory | [Description]
NH-bis(PEG4-Boc) is a Boc protected PEG reagent whiich is reactive with carboxylic acids, activated NHS esters,. Boc group can be removed under acidic conditions. | [Uses]
NH-bis(PEG4-C2-NH-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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