ChemicalBook--->CAS DataBase List--->2183440-65-3

2183440-65-3

2183440-65-3 Structure

2183440-65-3 Structure
IdentificationBack Directory
[Name]

FAM hydrazide, 6-isomer
[CAS]

2183440-65-3
[Synonyms]

FAM hydrazide, 6-isomer
[Molecular Formula]

C21H15ClN2O6
[MOL File]

2183440-65-3.mol
[Molecular Weight]

426.81
Chemical PropertiesBack Directory
[solubility ]

Soluble in DMF, DMSO, alcohols
[Appearance]

yellowororange solid
Hazard InformationBack Directory
[Description]

FAM hydrazide, 6-isomer is a Fluorescein dye linker containing a hydrazide group. Fluorescein is a universal dye. Hydrazide moieties react with aldehydes to form semi-permanent hydrazone bonds.
[Uses]

FAM hydrazide, 6-isomer hydrochloride is a hydrazide derivative of fluorescein (FAM). FAM is a xanthene dye, a parent of fluorescein dye series. FAM hydrazide, 6-isomer hydrochloride can be used for the labeling of carbonyl compounds, aldehydes, and ketones[1].
[References]

[1] Bieniarz C, et al. Thiolate and phosphorothioate functionalized fluoresceins and their use as fluorescent labels. Bioconjug Chem. 1994 Jan-Feb;5(1):31-9. DOI:10.1021/bc00025a005
[Abs/Em Maxima]

492/522 nm
[Fluoresene quantum yield]

0.93
[Extinction Coefficient]

74000
[CF260]

0.22
[CF280]

0.17
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