| Identification | Back Directory | [Name]
BDP 630/650 carboxylic acid | [CAS]
2183512-02-7 | [Synonyms]
BDP 630/650 carboxylic acid
BODIPY 630/650 carboxylic acid | [Molecular Formula]
C23H17BF2N2O3S | [MDL Number]
MFCD31580086 | [MOL File]
2183512-02-7.mol | [Molecular Weight]
450.27 |
| Chemical Properties | Back Directory | [solubility ]
Soluble in DMF, DMSO | [Appearance]
dark powder | [InChI]
InChI=1S/C23H17BF2N2O3S/c25-24(26)27-17(6-3-16-4-10-20(11-5-16)31-15-23(29)30)7-8-18(27)14-19-9-12-21(28(19)24)22-2-1-13-32-22/h1-14H,15H2,(H,29,30) | [InChIKey]
NPYDYOGYLPDKRP-UHFFFAOYSA-N | [SMILES]
[F-][B+3]1([N-]2C(=CC=C2C=C2C=CC(C3SC=CC=3)=N12)C=CC1C=CC(OCC(=O)[O-])=CC=1)[F-].[H+] |
| Hazard Information | Back Directory | [Description]
BDP 630/650 carboxylic acid is a BDP linker containing a carboxylic acid. The BDP 630/650 has a similar excitation and emission wavelengths to Cy5. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. | [Uses]
BDP 630/650 carboxylic acid is a bright far-red fluorophore based on a borondipyrromethene scaffold. BDP 630/650 carboxylic acid is a BDP linker containing carboxylic acid. BDP 630/650 carboxylic acid can react with primary amine groups to form a stable amide bond. (λex=630 nm, λem=650 nm)[1][2]. | [References]
[1] Lee A, et, al. Visualization of lipophagy using a supramolecular FRET pair. Chem Commun (Camb). 2021 Nov 16;57(91):12179-12182. DOI:10.1039/d1cc04779e
[2] Mitronova GY, et, al. High-Affinity Functional Fluorescent Ligands for Human β-Adrenoceptors. Sci Rep. 2017 Sep 26;7(1):12319. DOI:10.1038/s41598-017-12468-3 | [Abs/Em Maxima]
628/642 nm | [Fluoresene quantum yield]
0.91 | [Extinction Coefficient]
97000 | [CF260]
0.029 | [CF280]
0.035 |
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