ChemicalBook--->CAS DataBase List--->218916-51-9

218916-51-9

218916-51-9 Structure

218916-51-9 Structure
IdentificationBack Directory
[Name]

euphorbiafactor L2
[CAS]

218916-51-9
[Synonyms]

euphorbiafactor L2
PubChem ID: 101071473
15-O-Acetyleuphorbia factor L11
(2S,3S,4R,5R,7R,9S,11R,15R)-5,15-Diacetoxy-14-oxolathyra-6(17),12(E)-diene-3,7-diyl dibenzoate
4H-Cyclopenta[a]cyclopropa[f]cycloundecen-4-one, 4a,8-bis(acetyloxy)-7,10-bis(benzoyloxy)-1,1a,4a,5,6,7,7a,8,9,10,11,11a-dodecahydro-1,1,3,6-tetramethyl-9-methylene-, (1aR,2E,4aR,6S,7S,7aR,8R,10R,11aS)-
[Molecular Formula]

C38H42O9
[MDL Number]

MFCD32263220
[MOL File]

218916-51-9.mol
[Molecular Weight]

642.73
Chemical PropertiesBack Directory
[Boiling point ]

697.6±55.0 °C(Predicted)
[density ]

1.24±0.1 g/cm3(Predicted)
[storage temp. ]

4°C, protect from light
[solubility ]

DMSO: 83.33 mg/mL (129.65 mM)
[form ]

Solid
[color ]

White to off-white
[InChIKey]

AFRGWGGHJYMSDU-LVFBPYTJSA-N
[SMILES]

[C@]12([H])[C@@H](OC(=O)C3=CC=CC=C3)[C@@H](C)C[C@]1(OC(C)=O)C(=O)C(C)=C[C@@]1([H])C(C)(C)[C@@]1([H])C[C@@H](OC(=O)C1=CC=CC=C1)C(=C)[C@@H]2OC(C)=O |t:25|
Hazard InformationBack Directory
[Chemical Properties]

White crystalline powder, easily soluble in ethyl acetate, acetone, slightly soluble in petroleum ether, insoluble in water, derived from Euphorbia lathylris L.
[Uses]

Euphorbiafactor L2 has antitumor effect.
[Biological Activity]

Euphorbiafactor L2 is an erythrane diterpene (Euphorbia lathyris L.) isolated from Euphorbia seeds and has anticancer activity. It shows strong cytotoxicity and induces apoptosis through the mitochondrial pathway.
[storage]

4°C, protect from light
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