| Identification | Back Directory | [Name]
5-(3-Methoxyphenyl)-3-(5-Methyl-1,2,4-oxadiazol-3-yl)-1,6-Naphthyridin-2(1H)-one | [CAS]
219846-31-8 | [Synonyms]
AC-3933
Radequinil
5-(3-Methoxyphenyl)-3-(5-Methyl-1,2,4-oxadiazol-3-yl)-1,6-Naphthyridin-2(1H)-one
1,6-Naphthyridin-2(1H)-one, 5-(3-methoxyphenyl)-3-(5-methyl-1,2,4-oxadiazol-3-yl)- | [Molecular Formula]
C18H14N4O3 | [MDL Number]
MFCD13152356 | [MOL File]
219846-31-8.mol | [Molecular Weight]
334.33 |
| Chemical Properties | Back Directory | [storage temp. ]
4°C, away from moisture and light | [solubility ]
DMSO : 10 mg/mL (29.91 mM; ultrasonic and warming and heat to 60°C) | [form ]
Solid | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Uses]
Radequinil (AC-3933) is a benzodiazepine receptor (BzR) partial inverse agonist. AC-3933 binds to GABA(-) and GABA(+) ligand with Kis of 5.15 and 6.11 nM, respectively[1]. | [References]
[1] Hashimoto T, et al. Pharmacological properties of AC-3933, a novel benzodiazepine receptor partial inverse agonist. Neuroscience. 2014 Jan 3;256:352-9. DOI:10.1016/j.neuroscience.2013.10.031 |
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