| Identification | Back Directory | [Name]
BINUCLEINE 2 | [CAS]
220088-42-6 | [Synonyms]
Binucleine 2 - CAS 220088-42-6 - Calbiochem
N'-[2-(3-chloro-4-fluorophenyl)-4-cyanopyrazol-3-yl]-N,N-dimethylmethanimidamide | [Molecular Formula]
C13H11ClFN5 | [MDL Number]
MFCD00177827 | [MOL File]
220088-42-6.mol | [Molecular Weight]
291.71 |
| Chemical Properties | Back Directory | [Boiling point ]
456.9±55.0 °C(Predicted) | [density ]
1.30±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMSO: >5 mg/mL, soluble | [form ]
solid | [pka]
4.81±0.50(Predicted) | [Stability:]
Moisture Sensitive | [InChI]
1S/C13H11ClFN5/c1-19(2)8-17-13-9(6-16)7-18-20(13)10-3-4-12(15)11(14)5-10/h3-5,7-8H,1-2H3/b17-8+ | [InChIKey]
MNCYLHJHZOUDLB-CAOOACKPSA-N | [SMILES]
CN(C)\C=N\c1c(cnn1-c2ccc(F)c(Cl)c2)C#N |
| Hazard Information | Back Directory | [Uses]
Binucleine 2 is an inhibitor of cytokinesis function of the ARK-2 pathway. Highly isoform-specific inhibitor of Drosophila Aurora B kinase. | [Biological Activity]
Binucleine 2 is a cytokinesis inhibitor. | [IC 50]
Aurora B | [storage]
Store at -20°C |
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