ChemicalBook--->CAS DataBase List--->220088-42-6

220088-42-6

220088-42-6 Structure

220088-42-6 Structure
IdentificationBack Directory
[Name]

BINUCLEINE 2
[CAS]

220088-42-6
[Synonyms]

Binucleine 2 - CAS 220088-42-6 - Calbiochem
N'-[2-(3-chloro-4-fluorophenyl)-4-cyanopyrazol-3-yl]-N,N-dimethylmethanimidamide
[Molecular Formula]

C13H11ClFN5
[MDL Number]

MFCD00177827
[MOL File]

220088-42-6.mol
[Molecular Weight]

291.71
Chemical PropertiesBack Directory
[Boiling point ]

456.9±55.0 °C(Predicted)
[density ]

1.30±0.1 g/cm3(Predicted)
[storage temp. ]

2-8°C
[solubility ]

DMSO: >5 mg/mL, soluble
[form ]

solid
[pka]

4.81±0.50(Predicted)
[Stability:]

Moisture Sensitive
[InChI]

1S/C13H11ClFN5/c1-19(2)8-17-13-9(6-16)7-18-20(13)10-3-4-12(15)11(14)5-10/h3-5,7-8H,1-2H3/b17-8+
[InChIKey]

MNCYLHJHZOUDLB-CAOOACKPSA-N
[SMILES]

CN(C)\C=N\c1c(cnn1-c2ccc(F)c(Cl)c2)C#N
Safety DataBack Directory
[Symbol(GHS) ]

Corrosion (GHS05)Skull and Crossbones (GHS06)
GHS05,GHS06
[Signal word ]

Danger
[Hazard statements ]

H301-H318
[Precautionary statements ]

P280-P301+P310-P305+P351+P338
[Hazard Codes ]

T
[Risk Statements ]

25-41
[Safety Statements ]

26-39-45
[RIDADR ]

UN 2811 6.1/PG 3
[WGK Germany ]

3
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Uses]

Binucleine 2 is an inhibitor of cytokinesis function of the ARK-2 pathway. Highly isoform-specific inhibitor of Drosophila Aurora B kinase.
[Biological Activity]

Binucleine 2 is a cytokinesis inhibitor.
[IC 50]

Aurora B
[storage]

Store at -20°C
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