ChemicalBook--->CAS DataBase List--->220899-03-6

220899-03-6

220899-03-6 Structure

220899-03-6 Structure
IdentificationBack Directory
[Name]

METRAFENONE
[CAS]

220899-03-6
[Synonyms]

Metrafenone@100 μg/mL in Acetonitrile
Metrafenone@1000 μg/mL in Acetonitrile
(3-bromo-6-methoxy-2-methylphenyl)(2,3,4-trimethoxy-6-methyl...
Methanone, (3-bromo-6-methoxy-2-methylphenyl)(2,3,4-trimethoxy-6-methylphenyl)-
[Molecular Formula]

C19H21BrO5
[MDL Number]

MFCD08273825
[MOL File]

220899-03-6.mol
[Molecular Weight]

409.274
Chemical PropertiesBack Directory
[Boiling point ]

534.4±50.0 °C(Predicted)
[density ]

1.310±0.06 g/cm3(Predicted)
[form ]

neat
[Henry's Law Constant]

7.6×100 mol/(m3Pa) at 25℃, Maniere et al. (2011)
[Major Application]

agriculture
environmental
[InChI]

1S/C19H21BrO5/c1-10-9-14(23-4)18(24-5)19(25-6)15(10)17(21)16-11(2)12(20)7-8-13(16)22-3/h7-9H,1-6H3
[InChIKey]

AMSPWOYQQAWRRM-UHFFFAOYSA-N
[SMILES]

COc1ccc(Br)c(C)c1C(=O)c2c(C)cc(OC)c(OC)c2OC
[LogP]

5.190 (est)
[EPA Substance Registry System]

Methanone, (3-bromo-6-methoxy-2-methylphenyl)(2,3,4-trimethoxy-6-methylphenyl)- (220899-03-6)
Safety DataBack Directory
[Symbol(GHS) ]

Environment (GHS09)
GHS09
[Signal word ]

Warning
[Hazard statements ]

H410
[Precautionary statements ]

P273-P391-P501
[Hazard Codes ]

N
[Risk Statements ]

50/53
[Safety Statements ]

60-61
[RIDADR ]

UN 3077 9 / PGIII
[WGK Germany ]

3
[Storage Class]

11 - Combustible Solids
[Hazard Classifications]

Aquatic Acute 1
Aquatic Chronic 1
Hazard InformationBack Directory
[Uses]

Metrafenone is a fungicide used in pesticide formulations in the protection of vegetation and crops.
[Definition]

ChEBI: A member of the class of benzophenones that is benzophenone in which one of the phenyl groups is substituted by methoxy groups at positions 2, 3, and 4 and by a methyl group at position 6, while the other is substituted at positions 2, 3, and 6 by methyl, romine, and methoxy groups, respectively. A fungicide with protectant and curative properties, it is used for the control of powdery mildew in cereals and grape vines.
[Production Methods]

Metrafenone is commercially produced through a specialized organic synthesis process tailored for its use as a fungicide. While detailed production steps are proprietary and not widely disclosed, the synthesis typically involves constructing a benzophenone backbone with specific substitutions that confer antifungal activity. The process includes controlled reactions such as acylation and halogenation, followed by purification to achieve high chemical purity—often exceeding 99% for agricultural formulations.
[Mechanism of action]

Protective and curative action. Interferes with hyphal morphogenesis.
[Pesticide Type]

Fungicide
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