| Identification | Back Directory | [Name]
L-Alaninamide, N-[31-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1,29-dioxo-4,7,10,13,16,19,22,25-octaoxa-28-azahentriacont-1-yl]-L-valyl-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]methyl]phenyl]- | [CAS]
2210247-59-7 | [Synonyms]
Mal-Amido-PEG8-Val-Ala-PAB-PNP
Mal-amide-PEG8-Val-Ala-PAB-PNP
L-Alaninamide, N-[31-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1,29-dioxo-4,7,10,13,16,19,22,25-octaoxa-28-azahentriacont-1-yl]-L-valyl-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]methyl]phenyl]- | [Molecular Formula]
C48H68N6O19 | [MOL File]
2210247-59-7.mol | [Molecular Weight]
1033.08 |
| Chemical Properties | Back Directory | [Boiling point ]
1146.3±65.0 °C(Predicted) | [density ]
1.270±0.06 g/cm3(Predicted) | [form ]
Viscous Liquid | [pka]
13.30±0.70(Predicted) | [color ]
Colorless to light yellow |
| Hazard Information | Back Directory | [Uses]
Mal-amide-PEG8-Val-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. | [References]
[1] Junutula JR, et, al. Preparation of isoquinolidinobenzodiazepines and antibody conjugates thereof for treatment of hematological malignancies and solid tumors. WO2018053552 |
| Spectrum Detail | Back Directory | [Spectrum Detail]
L-Alaninamide, N-[31-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1,29-dioxo-4,7,10,13,16,19,22,25-octaoxa-28-azahentriacont-1-yl]-L-valyl-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]methyl]phenyl]-(2210247-59-7)1HNMR
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