| Identification | Back Directory | [Name]
EC-18 221139-79-3 | [CAS]
221139-79-3 | [Synonyms]
Mosedipimod
EC-18 221139-79-3
Mosedipimod EC-18
1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol
9,12-Octadecadienoic acid (9Z,12Z)-, 1-[(acetyloxy)methyl]-2-[(1-oxohexadecyl)oxy]ethyl ester | [Molecular Formula]
C39H70O6 | [MOL File]
221139-79-3.mol | [Molecular Weight]
634.97 |
| Chemical Properties | Back Directory | [Boiling point ]
650.6±35.0 °C(Predicted) | [density ]
0.947±0.06 g/cm3(Predicted) | [Cosmetics Ingredients Functions]
HUMECTANT
SKIN CONDITIONING
SKIN CONDITIONING - EMOLLIENT |
| Hazard Information | Back Directory | [Uses]
Mosedipimod is a monoacetyldiaglyceride that can be isolated from Cervus nippon Temminck. Mosedipimod is an orally active Toll-Like Receptor signaling inhibitor. Mosedipimod attenuates airway infammation by reducing myeloperoxidase expression in lung tissue. Mosedipimod is used in chronic obstructive pulmonary disease research[1]. | [References]
[1] Shin IS, et al. Protective effect of EC-18, a synthetic monoacetyldiglyceride on lung inflammation in a murine model induced by cigarette smoke and lipopolysaccharide. Int Immunopharmacol. 2016 Jan;30:62-68. DOI:10.1016/j.intimp.2015.11.025 |
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