| Identification | Back Directory | [Name]
2-Naphthaleneacetic acid, 6-[5-[[[(3,4-difluorophenyl)amino]carbonyl]amino]-2-pyrazinyl]-1,2,3,4-tetrahydro-1-oxo-2-(2,2,2-trifluoroethyl)-, (2S)- | [CAS]
2219321-25-0 | [Synonyms]
GSK2973980A
2-Naphthaleneacetic acid, 6-[5-[[[(3,4-difluorophenyl)amino]carbonyl]amino]-2-pyrazinyl]-1,2,3,4-tetrahydro-1-oxo-2-(2,2,2-trifluoroethyl)-, (2S)- | [Molecular Formula]
C25H19F5N4O4 | [MDL Number]
MFCD31813639 | [MOL File]
2219321-25-0.mol | [Molecular Weight]
534.43 |
| Hazard Information | Back Directory | [Uses]
GSK2973980A is a potent and selective Acyl-CoA:diacylglycerol acyltransferase 1 (DGAT1) inhibitor with an IC50 of 3 nM. | [References]
[1] Cheung M, et al. Discovery of Tetralones as Potent and Selective Inhibitors of Acyl-CoA:Diacylglycerol Acyltransferase 1. ACS Med Chem Lett. 2018 Jan 16;9(2):103-108. DOI:10.1021/acsmedchemlett.7b00450 |
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