| Identification | Back Directory | [Name]
N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-4-(2-fluorophenyl)-2-methyloxazole-5-carboxamide | [CAS]
2221010-42-8 | [Synonyms]
Dazcapistat
Proteasome,Dazcapistat,inhibit,Inhibitor
N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-4-(2-fluorophenyl)-2-methyloxazole-5-carboxamide
5-Oxazolecarboxamide, N-[3-amino-2,3-dioxo-1-(phenylmethyl)propyl]-4-(2-fluorophenyl)-2-methyl- | [Molecular Formula]
C21H18FN3O4 | [MDL Number]
MFCD34567624 | [MOL File]
2221010-42-8.mol | [Molecular Weight]
395.38 |
| Hazard Information | Back Directory | [Uses]
Dazcapistat is a potent calpain inhibitor, with IC50s of <3 μM for calpain 1, calpain 2 and calpain 9, respectively (patent WO2018064119A1, compound 405)[1]. | [References]
[1] Brad Owen BUCKMAN, et al. Calpain modulators and therapeutic uses thereof. WO2018064119A1. |
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