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2221948-98-5

2221948-98-5 Structure

2221948-98-5 Structure
IdentificationBack Directory
[Name]

Bis-PEG21-NHS ester
[CAS]

2221948-98-5
[Synonyms]

Di-NHS Ester-PEG21
Bis-dPEG21-NHS ester
4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,55,58,61,64-Heneicosaoxaheptahexacontanedioic acid, 1,67-bis(2,5-dioxo-1-pyrrolidinyl) ester
[Molecular Formula]

C54H96N2O29
[MDL Number]

MFCD21363289
[MOL File]

2221948-98-5.mol
[Molecular Weight]

1237.34
Chemical PropertiesBack Directory
[Boiling point ]

1004.0±75.0 °C(Predicted)
[density ]

1.24±0.1 g/cm3(Predicted)
[form ]

Solid-Liquid Mixture
[color ]

Colorless to off-white
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319
[Precautionary statements ]

P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330
Hazard InformationBack Directory
[Uses]

Bis-PEG21-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG21-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
[IC 50]

PEGs; Alkyl/ether; Cleavable Linker
[References]

[1] John L. Magnani, et al. Highly potent multimeric e-selectin antagonists. WO2018068010A1
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