| Identification | Back Directory | [Name]
Nonanoic acid, 9-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]- | [CAS]
2225148-51-4 | [Synonyms]
JUN 48514
Thalidomide-O-C8-COOH
Thalidomide-O-C8-acid
9-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)nonanoic acid
Nonanoic acid, 9-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]- | [Molecular Formula]
C22H26N2O7 | [MDL Number]
MFCD32063467 | [MOL File]
2225148-51-4.mol | [Molecular Weight]
430.45 |
| Hazard Information | Back Directory | [Uses]
Thalidomide-O-C8-COOH is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-O-C8-COOH (Cereblon ligand 3) can be connected to the ligand for protein by a linker to form PROTACs[1]. | [Biological Activity]
Thalidomide-O-C8-COOH is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-O-C8-COOH (Cereblon ligand 3) can be connected to the ligand for protein by a linker to form PROTACs[1]. | [IC 50]
Cereblon | [storage]
Store at -20°C | [References]
[1]. Nathanael S. Gray, et al. Degraders of wee1 kinase. WO2020069105A1. |
|
|