ChemicalBook--->CAS DataBase List--->2376990-31-5

2376990-31-5

2376990-31-5 Structure

2376990-31-5 Structure
IdentificationBack Directory
[Name]

Thalidomide-linker 15
[CAS]

2376990-31-5
[Synonyms]

Thalidomide-linker 15
-oxyacetamide-alkylC6-amine
Thalidomide-O-amido-C6-NH2 hydrochloride
N-(6-Aminohexyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide hydrochloride
ThalidomideOamidoC6NH2 hydrochloride,Inhibitor,inhibit,E3 Ligase Ligand-Linker Conjugates,Thalidomide-O-amido-C-6-NH2 hydrochloride,Thalidomide O amido C6 NH2 hydrochloride
[Molecular Formula]

C21H27ClN4O6
[MDL Number]

MFCD32692986
[MOL File]

2376990-31-5.mol
[Molecular Weight]

466.92
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[form ]

Solid
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

Thalidomide-O-amido-C6-NH2 hydrochloride, a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs[1].
[IC 50]

Cereblon
[storage]

Store at -20°C
[References]

[1] Bradner J, et al. Targeted protein degradation to attenuate adoptive t-cell therapy associated adverse inflammatory responses. WO 2017024318 A1
Spectrum DetailBack Directory
[Spectrum Detail]

Thalidomide-linker 15(2376990-31-5)1HNMR
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