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2226366-86-3

2226366-86-3 Structure

2226366-86-3 Structure
IdentificationBack Directory
[Name]

4-Piperidinecarboxamide, N-[3-(dimethylamino)propyl]-1-[2-(4-methylphenyl)-2H-pyrazolo[3,4-d]pyridazin-7-yl]-
[CAS]

2226366-86-3
[Synonyms]

TLR9-IN-1
4-Piperidinecarboxamide, N-[3-(dimethylamino)propyl]-1-[2-(4-methylphenyl)-2H-pyrazolo[3,4-d]pyridazin-7-yl]-
[Molecular Formula]

C23H31N7O
[MOL File]

2226366-86-3.mol
[Molecular Weight]

421.54
Chemical PropertiesBack Directory
[density ]

1.26±0.1 g/cm3(Predicted)
[form ]

Solid
[pka]

15.60±0.20(Predicted)
[color ]

Off-white to light yellow
Hazard InformationBack Directory
[Uses]

TLR9-IN-1 is a potent and selective TLR9 inhibitor with an IC50 value of 7 nM for human TLR9. TLR9-IN-1 can be used for researching diseases associated with undesirable immune response[1].
[IC 50]

human TLR9: 7 nM (IC50)
[References]

[1] Albert Frederick Candia, et al. Toll-like receptor antagonist compounds and methods of use. WO2018089695
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