| Identification | Back Directory | [Name]
Imidazo[1,2-a]pyrimido[5,4-e]pyrimidin-5(6H)-one, 6-(2,6-dichlorophenyl)-8,9-dihydro-2-[[3-methyl-4-[(3R,5S)-3,4,5-trimethyl-1-piperazinyl]phenyl]amino]-, rel- | [CAS]
2226938-19-6 | [Synonyms]
WEE1-IN-10
Imidazo[1,2-a]pyrimido[5,4-e]pyrimidin-5(6H)-one, 6-(2,6-dichlorophenyl)-8,9-dihydro-2-[[3-methyl-4-[(3R,5S)-3,4,5-trimethyl-1-piperazinyl]phenyl]amino]-, rel- | [Molecular Formula]
C28H30Cl2N8O | [MOL File]
2226938-19-6.mol | [Molecular Weight]
565.5 |
| Hazard Information | Back Directory | [Uses]
WEE1-IN-10 (compound 77) is a Wee1 kinase inhibitor. WEE1-IN-10 shows inhibitory activity on LOVO cell growth, with an IC50 of 0.524 μM. WEE1-IN-10 can be used for the research of diseases caused by abnormal activity of Wee1[1]. | [References]
[1] CAI Suixiong, et al. 8,9-dihydroimidazole[1,2-a]pyrimido[5,4-e]pyrimidine-5(6h)-ketone compound. Patent. WO2018090939A1. |
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