ChemicalBook--->CAS DataBase List--->2227450-68-0

2227450-68-0

2227450-68-0 Structure

2227450-68-0 Structure
IdentificationBack Directory
[Name]

5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-N-(2-(2-(prop-2-yn-1-yloxy)ethoxy)ethyl)pentanamide
[CAS]

2227450-68-0
[Synonyms]

5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-N-(2-(2-(prop-2-yn-1-yloxy)ethoxy)ethyl)pentanamide
[Molecular Formula]

C17H27N3O4S
[MDL Number]

MFCD31922733
[MOL File]

2227450-68-0.mol
[Molecular Weight]

369.479
Chemical PropertiesBack Directory
[Boiling point ]

669.5±55.0 °C(Predicted)
[density ]

1.169±0.06 g/cm3(Predicted)
[solubility ]

soluble in water, DMSO, DCM, DMF
[pka]

13.90±0.40(Predicted)
[Appearance]

white powder
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P280-P301+P312-P302+P352-P305+P351+P338
Hazard InformationBack Directory
[Description]

Biotin-PEG2-alkyne is a click chemistry biotinylation tool. This reagent allows the labeling of azide-containing molecules with biotin via copper-catalyzed click reaction. Biotin-labeled biomolecules can be bound to avidin or streptavidin for further purification and detection.


This structure of biotin alkyne features a hydrophilic PEG2 linker that separates biotin residue from the target molecule for efficient binding with streptavidin. Its linker also enhances aqueous solubility to facilitate conjugation.

[Uses]

Biotin-PEG2-alkyne is a short PEG linker featuring a biotin group and a terminal alkyne. Biotin is useful for affinity-based applications such as pull-down assays while terminal alkynes are used in copper (I) click chemistry with azides.
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