ChemicalBook--->CAS DataBase List--->2230212-27-6

2230212-27-6

2230212-27-6 Structure

2230212-27-6 Structure
IdentificationBack Directory
[Name]

Sulfo-Cy5 NHS Methyl type | Lumiprobe type
[CAS]

2230212-27-6
[Synonyms]

ulfo-Cy5 NHS Methyl type
MeCY5-NHS ester potassium
Sulfo-Cy5 NHS Me, Cyanine5 NHS Me
Sulfo-Cyanine5 NHS ester potassium
Sulfo-Cy5 NHS Methyl type | Lumiprobe type
Potassium 1-(6-((2,5-dioxopyrrolidin-1-yl)oxy)-6-oxohexyl)-3,3-dimethyl-2-(5-(1,3,3-trimethyl-5-sulfonatoindolin-2-ylidene)penta-1,3-dien-1-yl)-3H-indol-1-ium-5-sulfonate
[Molecular Formula]

C36H42KN3O10S2
[MDL Number]

MFCD30527435
[MOL File]

2230212-27-6.mol
[Molecular Weight]

779.96
Chemical PropertiesBack Directory
[solubility ]

Soluble in Water, DMSO, DMF, DCM
[Appearance]

Dark blue solid
[ex/em]

649/672 nm (PBS buffer)
[ε(extinction coefficient)]

271000 L⋅mol−1⋅cm−1
[Φ(quantum yield)]

0.28
[InChIKey]

XSUITALZBVEBJZ-UHFFFAOYSA-N
[SMILES]

C([N+]1=C(C(C)(C)C2=CC(S([O-])(=O)=O)=CC=C12)C=CC=CC=C1N(C2=CC=C(S(O)(=O)=O)C=C2C1(C)C)C)CCCCC(=O)ON1C(CCC1=O)=O.[KH]
Hazard InformationBack Directory
[Description]

Cy5 dyes are one type of the most common red fluorophores. Its max. absorbance/emission max is 646/665nm. They are widely used for labeling peptides, proteins and oligos etc. Cy5 NHS ester dyes are recommended for labeling amine containing biomolecules under pH 7.4 -9.0.
[Chemical Properties]

Appearance: Dark blue solid
ex/em: 649/672 nm (PBS buffer)
Extinction coefficient (ε): 271000 L??mol??1??cm??1
Quantum yield (Φ): 0.28
[Uses]

MeCY5-NHS ester (potassium) is a reactive dye and can be used for labeling protein nucleic acid[1].
[References]

[1] Shukla S,et al. Antibody Response against Cowpea Mosaic Viral Nanoparticles Improves In Situ Vaccine Efficacy in Ovarian Cancer. ACS Nano. 2020;14(3):2994-3003. DOI:10.1021/acsnano.9b07865
[Abs/Em Maxima]

646/662 nm
[Fluoresene quantum yield]

0.28
[Extinction Coefficient]

271000
[CF260]

0.04
[CF280]

0.04
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