| Identification | Back Directory | [Name]
3H-IndoliuM, 2-[5-[1-[6-[(3-azidopropyl)aMino]-6-oxohexyl]-1,3-dihydro-3,3-diMethyl-5-sulfo-2H-indol-2-ylidene]-1,3-pentadien-1-yl]-1,3,3-triMethyl-5-sulfo-, inner salt | [CAS]
1481447-40-8 | [Synonyms]
Cy5-N3
CY3-N3
Sulfo-Cy5-N3
Sulfo-Cy5-N3, >97%
3H-IndoliuM, 2-[5-[1-[6-[(3-azidopropyl)aMino]-6-oxohexyl]-1,3-dihydro-3,3-diMethyl-5-sulfo-2H-indol-2-ylidene]-1,3-pentadien-1-yl]-1,3,3-triMethyl-5-sulfo-, inner salt | [Molecular Formula]
C35H44N6O7S2 | [MDL Number]
MFCD32062578 | [MOL File]
1481447-40-8.mol | [Molecular Weight]
724.89 |
| Chemical Properties | Back Directory | [solubility ]
易溶于甲醇，DMF等有机溶剂，极易溶于水 | [form ]
Solid | [color ]
Brown to dark brown | [Appearance]
Dark blue solid | [ex/em]
649/672 nm (PBS buffer) | [ε(extinction coefficient)]
271000 L⋅mol−1⋅cm−1 | [Φ(quantum yield)]
0.28 |
| Hazard Information | Back Directory | [Uses]
Sulfo-Cy5-N3 is a click chemistry reagent containing an azide group. Cy5 is a red fluorescent label dye for imaging (Ex/Em=642/670 nm)[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. | [References]
[1] An F, et al. Small ultra-red fluorescent protein nanoparticles as exogenous probes for noninvasive tumor imaging in vivo. Int J Biol Macromol. 2020 Jun 15;153:100-106. DOI:10.1016/j.ijbiomac.2020.02.253 |
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