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2232890-86-5

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2232890-86-5 Structure

2232890-86-5 Structure

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[Name] Benzenesulfonamide, 3-(4-benzoyl-2-ethyl-2,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl)-
[CAS] 2232890-86-5
[Synonyms] TK4g Benzenesulfonamide, 3-(4-benzoyl-2-ethyl-2,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl)-
[Molecular Formula] C19H19N3O4S
[MOL File] 2232890-86-5.mol
[Molecular Weight] 385.44

Chemical Properties	Back Directory
[Boiling point ] 580.8±60.0 °C(Predicted)
[density ] 1.355±0.06 g/cm3(Predicted)
[pka] 10.02±0.60(Predicted)

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[Uses] TK4g is a Janus kinase (JAK) inhibitor with the IC50 values of 12.61 nM and 15.80 nM for JAK2 and JAK3, respectively. TK4g can be used in lymphoid-derived diseases and leukemia cancer research[1].
[IC 50] JAK2: 12.61 nM (IC₅₀); JAK3: 15.80 nM (IC₅₀)
[References] [1] Kamonpan Sanachai, et al. Pharmacophore-Based Virtual Screening and Experimental Validation of Pyrazolone-Derived Inhibitors toward Janus Kinases. ACS Omega 2022.

2232890-86-5 suppliers list

Company Name:	TargetMol Chemicals Inc.
Telephone:	15002134094
Website:	https://www.targetmol.cn/

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