| Identification | Back Directory | [Name]
Benzamide, 2-[[2,6-dichloro-4-(3,5-dimethyl-1H-pyrazol-4-yl)phenyl]amino]-N-hydroxy- | [CAS]
2243944-92-3 | [Synonyms]
UUN44923
FTO-IN-1
Dac51，UUN-44923
Benzamide, 2-[[2,6-dichloro-4-(3,5-dimethyl-1H-pyrazol-4-yl)phenyl]amino]-N-hydroxy- | [Molecular Formula]
C18H16Cl2N4O2 | [MDL Number]
MFCD34473341 | [MOL File]
2243944-92-3.mol | [Molecular Weight]
391.25 |
| Chemical Properties | Back Directory | [density ]
1.448±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: 100 mg/mL (197.91 mM);Water: Insoluble;Ethanol: Insoluble | [pka]
8.72±0.40(Predicted) |
| Hazard Information | Back Directory | [Description]
UUN44923 is a FTO inhibitor. UUN44923 may be useful for treating diseases assocd. with FTO targets, obesity, metabolic syndrome (MS)?, type 2 diabetes (T2D)?, Alzheimer's diseases, breast cancers, small-?cell lung cancers, a human bone marrow striated muscle cancer, a pancreatic cancer, malignant glioblastoma and the like. UUN44923 was reported in WO 2018157843. This product has no formal name at the moment. | [Uses]
FTO-IN-1 is a fat mass and obesity-associated enzyme (FTO) inhibitor extracted from patent WO2018157843A1, compound 32, with an IC50 of <1 μM. FTO-IN-1 can be used for the research of cancer[1]. | [storage]
Store at -20°C | [References]
[1] Yang C, et, al. 2-(substituted benzene matrix) aromatic formate fto inhibitor, preparation method therefor, and applications thereof. WO2018157843A1. |
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| Company Name: |
Bide Pharmatech Ltd.
|
| Telephone: |
400-1647117 13681763483 |
| Website: |
https://www.bidepharm.com/ |
| Company Name: |
InvivoChem
|
| Telephone: |
13549236410 |
| Website: |
https://www.invivochem.cn/ |
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