| Identification | Back Directory | [Name]
DM4-SPDP | [CAS]
2245698-48-8 | [Synonyms]
DM4-SPDP
Maytansine, N2'-deacetyl-N2'-[4-[[3-[(2,5-dioxo-1-pyrrolidinyl)oxy]-3-oxopropyl]dithio]-4-methyl-1-oxopentyl]- | [Molecular Formula]
C45H61ClN4O14S2 | [MDL Number]
MFCD28400105 | [MOL File]
2245698-48-8.mol | [Molecular Weight]
981.57 |
| Hazard Information | Back Directory | [Uses]
(R)-DM4-SPDP is a conjugate made up of the linker SPDP and the toxic molecule DM4, and it can be used to prepare antibody-drug conjugates[1]. | [storage]
Store at -20°C | [References]
[1] Silvana T Tivadar, et al. Monoclonal Antibody Targeting Sialyl-di-Lewisa-Containing Internalizing and Noninternalizing Glycoproteins with Cancer Immunotherapy Development Potential. Mol Cancer Ther. 2020 Mar;19(3):790-801. DOI:10.1158/1535-7163.MCT-19-0221 |
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