| Identification | Back Directory | [Name]
Gymnemagenin | [CAS]
22467-07-8 | [Synonyms]
GYMNEMAGENIN(SH)
Olean-12-ene-3beta,16beta,21beta,22alpha,23,28-hexol | [Molecular Formula]
C30H50O6 | [MDL Number]
MFCD06656306 | [MOL File]
22467-07-8.mol | [Molecular Weight]
506.71 |
| Chemical Properties | Back Directory | [Melting point ]
330-331℃ | [Boiling point ]
634.5±55.0 °C(Predicted) | [density ]
1.23 | [storage temp. ]
2-8°C | [solubility ]
DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS (pH 7.2)(1:2): 0.3 mg/ml | [form ]
neat | [pka]
14.03±0.70(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Gymnemagenin is a saponin with a triterpenoid structure, purported to display hypoglycemic and antioxidant effects. | [in vivo]
Gymnemagenin has a poor oral bioavailability (~ 14 %) in rats[2].
Gymnemagenin has a short half-life and a high clearance in rats[2].
Gymnemagenin metabolizes rapidly with a short apparent and intrinsic half-life (~ 7 min) and high intrinsic clearance[2].
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