| Identification | Back Directory | [Name]
Benzamide, 4-[(2S,3R)-2-(4-chlorophenyl)-3-(1-methylethyl)-4-oxo-1-azetidinyl]-N-[[4-(ethylsulfonyl)phenyl]methyl]- | [CAS]
2247083-47-0 | [Synonyms]
RORγt modulator 2
Benzamide, 4-[(2S,3R)-2-(4-chlorophenyl)-3-(1-methylethyl)-4-oxo-1-azetidinyl]-N-[[4-(ethylsulfonyl)phenyl]methyl]- | [Molecular Formula]
C28H29ClN2O4S | [MOL File]
2247083-47-0.mol | [Molecular Weight]
525.06 |
| Hazard Information | Back Directory | [Uses]
RORγt modulator 2 (Compound 21) is a modulator of retinoid-related orphan receptor γt (RORγt) with the IC50 of <50 nM. RORγt modulator 2 can be used for the research of RORyt mediated diseases such as, e.g., pain, inflammation, COPD, asthma, rheumatoid arthritis, colitis, multiple sclerosis, psoriasis, neurodegenerative diseases and cancer[1]. | [References]
[1] V. S. Prasada Rao Lingam, et al. Substituted oxoazetidine analogues as ror gamma modulators. |
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