| Identification | More | [Name]
1-(4-Fluorophenyl)piperazine | [CAS]
2252-63-3 | [Synonyms]
1-(4-FLUOROPHENYL)PIPERAZINE
1-(P-FLUOROPHENYL)PIPERAZINE
4-FLUOROPHENYLPIPERAZINE
AKOS BBS-00003614
LABOTEST-BB LT00053495
N-(4-FLUOROPHENYL)PIPERAZINE
RARECHEM AH CK 0104
TIMTEC-BB SBB000218
Piperazine, 1-(4-fluorophenyl)-
4-(1-Piperazino)fluorobenzene
1-(4-Fluorophenyl)piperazine 97%
1-(4-Fluorophenyl)piperazine97%
FLUOROPHENYL PIPERAZINE
TRIFLUOROETHOXY FLUOROPHENYL PIPERAZINE
1-(4-Fluorophenyl)piperazine ,98%
4-(4-Fluorophenyl)piperazine | [EINECS(EC#)]
218-846-6 | [Molecular Formula]
C10H13FN2 | [MDL Number]
MFCD00005960 | [Molecular Weight]
180.22 | [MOL File]
2252-63-3.mol |
| Chemical Properties | Back Directory | [Appearance]
clear yellowish liquid after melting | [Melting point ]
30-33 °C (lit.) | [Boiling point ]
118-123 °C/0.1 mmHg (lit.) | [density ]
1.0 | [refractive index ]
1.5585-1.5605
| [Fp ]
>230 °F
| [storage temp. ]
Refrigerator | [solubility ]
Chloroform (Slightly), Ethyl Acetate (Slightly) | [form ]
Liquid After Melting | [pka]
8.93±0.10(Predicted) | [color ]
Clear yellow | [Water Solubility ]
Insoluble in water. | [Sensitive ]
Air Sensitive | [BRN ]
610723 | [InChI]
1S/C10H13FN2/c11-9-1-3-10(4-2-9)13-7-5-12-6-8-13/h1-4,12H,5-8H2 | [InChIKey]
AVJKDKWRVSSJPK-UHFFFAOYSA-N | [SMILES]
Fc1ccc(cc1)N2CCNCC2 | [CAS DataBase Reference]
2252-63-3(CAS DataBase Reference) | [NIST Chemistry Reference]
1-(P-fluorophenyl)piperazine(2252-63-3) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,T,C | [Risk Statements ]
R22:Harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin .
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [RIDADR ]
2811 | [WGK Germany ]
2
| [Hazard Note ]
Toxic/Corrosive | [HazardClass ]
8 | [PackingGroup ]
III | [HS Code ]
29339900 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| Hazard Information | Back Directory | [Chemical Properties]
clear yellowish liquid after melting | [Uses]
1-(4-Fluorophenyl)piperazine is a major metabolite of Niaparazine, a sedative, hypnotic drug. Metabolites of Niaprazine occurred by N-dealkylation, N-dearylation, aromatic hydroxylation and N-oxidatio
n. | [Uses]
1-(4-Fluorophenyl)piperazine was used in the synthesis of N,N-disubstituted piperazine. It is a major metabolite of niaparazine, a sedative, a hypnotic drug. | [Synthesis]
Weighing 4-fluoroaniline 9.2mL (0.10mol), bis(2-chloroethyl)amine hydrochloride 17.85g (0.10mol) and diethylene glycol monomethyl ether 25mL in a 100mL three-necked flask, and placed in the reflux device equipped with a reflux device WBFY-201-type microco |
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