| Identification | Back Directory | [Name]
Pyrazolo[1,5-a]pyrimidine-3-carboxamide, N-[3-[5-chloro-2-(difluoromethoxy)phenyl]-1-[2-(dimethylamino)-2-oxoethyl]-1H-pyrazol-4-yl]- | [CAS]
2252277-73-7 | [Synonyms]
GDC-4379
Pyrazolo[1,5-a]pyrimidine-3-carboxamide, N-[3-[5-chloro-2-(difluoromethoxy)phenyl]-1-[2-(dimethylamino)-2-oxoethyl]-1H-pyrazol-4-yl]- | [Molecular Formula]
C21H18ClF2N7O3 | [MOL File]
2252277-73-7.mol | [Molecular Weight]
489.86 |
| Chemical Properties | Back Directory | [density ]
1.52±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 31.25 mg/mL (63.79 mM; Need ultrasonic) | [form ]
Solid | [pka]
8.50±0.46(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Uses]
GDC-4379 is a JAK1 inhibitor that can be used for the research of asthma[1]. | [References]
[1] Stumpf A, et, al. Efficient, Protecting Group Free Kilogram-Scale Synthesis of the JAK1 Inhibitor GDC-4379. Org. Process Res. Dev. 2021, 25, 11, 2537-2550. |
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