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2259851-38-0

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2259851-38-0 Structure

2259851-38-0 Structure
IdentificationBack Directory
[Name]

3-((4-(Piperidin-4-yl)phenyl)amino)piperidine-2,6-dione hydrochloride
[CAS]

2259851-38-0
[Synonyms]

3-((4-(Piperidin-4-yl)phenyl)amino)piperidine-2,6-dione hydr
3-((4-(Piperidin-4-yl)phenyl)amino)piperidine-2,6-dione hydrochloride
Chemical PropertiesBack Directory
[storage temp. ]

2-8°C
[form ]

powder
[Appearance]

Off-white to light brown Solid
[SMILES]

O=C1NC(C(NC2=CC=C(C=C2)C3CCNCC3)CC1)=O.[xHCl]
Safety DataBack Directory
[WGK Germany ]

WGK 3
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Uses]

A functionalized cereblon ligand for development of Thalidomide based PROTACs. Allows rapid conjugation with carboxyl linkers due to presence of amine group via peptide coupling reactions. Amenable for linker attachement via reductive amination, and a basic building block for making protein degrader library.

Technology Spotlight:

Degrader Building Blocks for Targeted Protein Degradation

Protein Degrader Building Blocks
Spectrum DetailBack Directory
[Spectrum Detail]

3-((4-(Piperidin-4-yl)phenyl)amino)piperidine-2,6-dione hydrochloride(2259851-38-0)1HNMR
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