2654822-04-3

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2654822-04-3 Structure

Identification	Back Directory
[Name] 2,6-Piperidinedione, 3-[[3-fluoro-4-(4-piperidinyl)phenyl]amino]-, hydrochloride (1:1)
[CAS] 2654822-04-3
[Synonyms] 3-((3-Fluoro-4-(piperidin-4-yl)phenyl)amino)piperidine-2,6-dione hydrochloride 2,6-Piperidinedione, 3-[[3-fluoro-4-(4-piperidinyl)phenyl]amino]-, hydrochloride (1:1)
[Molecular Formula] C16H21ClFN3O2
[MOL File] 2654822-04-3.mol
[Molecular Weight] 341.81

Chemical Properties	Back Directory
[storage temp. ] 2-8°C
[form ] powder or crystals
[color ] off-white to beige
[InChI] 1S/C16H20FN3O2.ClH/c17-13-9-11(19-14-3-4-15(21)20-16(14)22)1-2-12(13)10-5-7-18-8-6-10;/h1-2,9-10,14,18-19H,3-8H2,(H,20,21,22);1H
[InChIKey] VJQKECGXGMCYHY-UHFFFAOYSA-N
[SMILES] Cl.O=C1NC(=O)C(NC2=CC=C(C(F)=C2)C3CCNCC3)CC1

Safety Data	Back Directory
[WGK Germany ] WGK 3
[Storage Class] 11 - Combustible Solids

[Uses]

A functionalized cereblon ligand for development of Thalidomide based PROTACs. Allows rapid conjugation with carboxyl linkers due to presence of amine group via peptide coupling reactions. Amenable for linker attachment via reductive amination, and a basic building block for making protein degrader library.

Technology Spotlight:

targeted protein degradation
When used with other protein degrader building blocks
Degrader Building Blocks for Targeted Protein Degradation
Protein Degrader Building Blocks

2654822-04-3 suppliers list

Company Name:	Daicel Chiral Technologies (China)CO.,LTD
Tel:	021-50460086-9 15921403865
Website:	http://www.daicelchiraltech.cn/reagents/Default.aspx

Company Name:	Jilin Province Woda Biotechnology Co., Ltd.
Tel:	13504435624
Website:	https://www.wodapro.com

Company Name:	Shanghai Haohong Scientific Co., Ltd.
Tel:	400-8210725 4008210725
Website:	https://www.leyan.com/

Company Name:	Aikon International Limited
Tel:	025-58859352 18651614124
Website:	https://www.aikonchem.com/

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