| Chemical Properties | Back Directory | [density ]
1.414±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 125 mg/mL (206.92 mM) | [form ]
Solid | [pka]
8.27±0.20(Predicted) | [color ]
Light yellow to yellow | [InChIKey]
STPSLAZMEWZDAJ-JKXWNSIXNA-N | [SMILES]
[C@H](C1C=CC=CC=1OC)(NS(C1=C(C=C2NC(=O)C=CC2=C1)Cl)(=O)=O)C(=O)N(CC(=O)OCC)CC1SC=CC=1 |&1:0,r| |
| Hazard Information | Back Directory | [Uses]
OSMI-4 is a low nanomolar O-GlcNAc transferase (OGT) inhibitor, with an EC50 of 3 μM in cells. | [References]
[1] Martin SES, et al. Structure-Based Evolution of Low Nanomolar O-GlcNAc Transferase Inhibitors. J Am Chem Soc. 2018 Oct 24;140(42):13542-13545. DOI:10.1021/jacs.8b07328 |
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