| Identification | Back Directory | [Name]
METHYL 3-THIOPHENECARBOXYLATE 97 | [CAS]
22913-26-4 | [Synonyms]
THOO1
3-Methoxycarbonylthiophene
Methyl 3-thiophenecarboxylate
Methyl thiophene-3-carboxylate
METHYL 3-THIOPHENECARBOXYLATE 97
Methyl Thiophene-3-carboxylate >
3- thiophene carboxylic acidMethyl ester
Thiophene-3-carboxylic acid methyl ester
METHYL 3-THIOPHENECARBOXYLATE 97 ISO 9001：2015 REACH | [Molecular Formula]
C6H6O2S | [MDL Number]
MFCD06203810 | [MOL File]
22913-26-4.mol | [Molecular Weight]
142.18 |
| Chemical Properties | Back Directory | [Boiling point ]
98 °C10 mm Hg(lit.)
| [density ]
1.174 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.5380(lit.)
| [Fp ]
172 °F
| [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [form ]
clear liquid | [color ]
Colorless to Light yellow | [λmax]
239nm(Hexane)(lit.) |
| Hazard Information | Back Directory | [Chemical Properties]
Colorless to yellow liquid | [Synthesis]
A catalytic amount of concentrated sulfuric acid (0.5 mL) was added to a solution of 3-thiophenecarboxylic acid (2.0 g, 15.60 mmol) in methanol (30 mL), and the reaction mixture was heated to reflux for 2 hours. After completion of the reaction, the solvent was removed by distillation under reduced pressure. The residue was poured into ice-cold water and extracted with ethyl acetate (3 × 20 mL). The organic layers were combined, washed with saturated brine and dried over anhydrous sodium sulfate. After filtration, the organic phase was concentrated under reduced pressure to give methyl 3-thiophenecarboxylate (1.8 g, 81% yield) as a colorless oil. | [References]
[1] Patent: WO2006/123145, 2006, A1. Location in patent: Page/Page column 44
[2] Recueil des Travaux Chimiques des Pays-Bas, 1934, vol. 53, p. 643,648
[3] Recueil des Travaux Chimiques des Pays-Bas, 1936, vol. 55, p. 991
[4] Patent: WO2016/115013, 2016, A1. Location in patent: Page/Page column 70
[5] Patent: WO2006/108701, 2006, A1. Location in patent: Page/Page column 61 |
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