| Identification | More | [Name]
METHYL 3-AMINOTHIOPHENE-4-CARBOXYLATE HYDROCHLORIDE | [CAS]
39978-14-8 | [Synonyms]
METHYL 3-AMINOTHIOPHENE-4-CARBOXYLATE HYDROCHLORIDE
METHYL 4-AMINOTHIOPHENE-3-CARBOXYLATE HYDROCHLORIDE
methyl4-aminothiophene-3-carboxylateHCl
Methyl 3-aminothiophene-4-carboxylate hydrochloride, 97+% | [Molecular Formula]
C6H8ClNO2S | [MDL Number]
MFCD00068149 | [Molecular Weight]
193.65 | [MOL File]
39978-14-8.mol |
| Chemical Properties | Back Directory | [Melting point ]
203-204°C | [storage temp. ]
Keep in dark place,Inert atmosphere,2-8°C | [form ]
Powder | [color ]
Brown | [Sensitive ]
Hygroscopic | [InChI]
InChI=1S/C6H7NO2S.ClH/c1-9-6(8)4-2-10-3-5(4)7;/h2-3H,7H2,1H3;1H | [InChIKey]
JGIRDDQLZLXRKQ-UHFFFAOYSA-N | [SMILES]
C1(C(=O)OC)=CSC=C1N.Cl | [CAS DataBase Reference]
39978-14-8(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . | [Hazard Note ]
Irritant | [HS Code ]
2934999090 |
| Hazard Information | Back Directory | [Uses]
Methyl 3-aminothiophene-4-carboxylate hydrochloride is used in the preparation of ethyl (4-methoxycarbonyl)thiophene-3-carbamate by reacting with carbonochloridic acid ethyl ester. | [Synthesis]
a. Michael addition of methyl thioglycolate with methyl acrylate yields methyl 3-[(methoxycarbonyl)methylthio]propionate.
b. The product from step a cyclizes in the presence of sodium methoxide to give methyl 4-oxo-2,3,5-trihydroxythiophene-3-carboxyla |
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