| Identification | Back Directory | [Name]
PROTAC Mcl1-binding moiety 1 | [CAS]
2351218-72-7 | [Synonyms]
A-1210477-piperazinyl
PROTAC Mcl1-binding moiety 1
1H-Indole-2-carboxylic acid, 7-[5-[[4-[4-[(dimethylamino)sulfonyl]-1-piperazinyl]phenoxy]methyl]-1,3-dimethyl-1H-pyrazol-4-yl]-3-[3-(1-naphthalenyloxy)propyl]-1-[2-(1-piperazinyl)ethyl]- | [Molecular Formula]
C46H56N8O6S | [MDL Number]
MFCD32263023 | [MOL File]
2351218-72-7.mol | [Molecular Weight]
849.05 |
| Hazard Information | Back Directory | [Uses]
A-1210477-piperazinyl is a compound binds to protein myeloid cell leukemia 1 (MCL1) used for PROTAC technology[1]. | [References]
[1] Papatzimas JW, et al. From Inhibition to Degradation: Targeting the Antiapoptotic Protein Myeloid Cell Leukemia 1 (MCL1). J Med Chem. 2019 Jun 13;62(11):5522-5540. DOI:10.1021/acs.jmedchem.9b00455 |
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