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2353409-48-8

2353409-48-8 Structure

2353409-48-8 Structure
IdentificationBack Directory
[Name]

TCO-PEG2-Sulfo-NHS ester
[CAS]

2353409-48-8
[Synonyms]

TCO-PEG2-Sulfo-NHS ester
[Molecular Formula]

C28H49N5O12S
[MDL Number]

MFCD32069536
[MOL File]

2353409-48-8.mol
[Molecular Weight]

679.78
Chemical PropertiesBack Directory
[solubility ]

Soluble in Water, DMSO, DMF
Hazard InformationBack Directory
[Description]

TCO-PEG2-Sulfo-NHS ester is a PEG linker containing a TCO moiety and a sulfo-NHS ester moiety. The sulfo group makes this molecule soluble in waqueous buffer. This reagent can be used to label antibodies, proteins and other primary amine-containing macromolecules with TCO moiety.
[Uses]

TCO-PEG2-Sulfo-NHS ester-EDC Urea is a click chemistry reagent containing an azide group. TCO-PEG2-Sulfo-NHS ester is a PEG linker containing a TCO moiety and a sulfo-NHS ester moiety. The sulfo group makes this molecule soluble in waqueous buffer. This reagent can be used to label antibodies, proteins and other primary amine-containing macromolecules with TCO moiety. Reagent grade, for research use only[1]. TCO-PEG2-Sulfo-NHS ester-EDC Urea is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
[References]

[1] Jiang X, et al. Recent applications of click chemistry in drug discovery. Expert Opin Drug Discov. 2019 Aug;14(8):779-789. DOI:10.1080/17460441.2019.1614910
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