| Identification | Back Directory | [Name]
Propanamide, N-[(1S)-3-amino-1-cyano-3-oxopropyl]-2,2-dimethyl-3-[[4-(1-methyl-1H-indazol-5-yl)phenyl]sulfonyl]- | [CAS]
2361157-34-6 | [Synonyms]
Legumain inhibitor 1
Propanamide, N-[(1S)-3-amino-1-cyano-3-oxopropyl]-2,2-dimethyl-3-[[4-(1-methyl-1H-indazol-5-yl)phenyl]sulfonyl]- | [Molecular Formula]
C23H25N5O4S | [MOL File]
2361157-34-6.mol | [Molecular Weight]
467.54 |
| Chemical Properties | Back Directory | [Boiling point ]
836.4±65.0 °C(Predicted) | [density ]
1.34±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
12.29±0.46(Predicted) | [color ]
White to yellow |
| Hazard Information | Back Directory | [Uses]
Legumain inhibitor 1 is a potent and selective Legumain inhibitor with an IC50 of 3.6 nM. Legumain inhibitor 1 can be used for cancer research[1]. | [References]
[1] Sharon L Eddie, et al. Identification and SAR exploration of a novel series of Legumain inhibitors. Bioorg Med Chem Lett. 2019 Jun 15;29(12):1546-1548. DOI:10.1016/j.bmcl.2019.03.019 |
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