| Chemical Properties | Back Directory | [Boiling point ]
406.8±30.0 °C(Predicted) | [density ]
1.180±0.06 g/cm3(Predicted) | [form ]
Oil | [pka]
9.86±0.46(Predicted) | [color ]
Colorless to light yellow |
| Hazard Information | Back Directory | [Uses]
malonyl-NAC increases cellular propylation, resulting in reduced endogenous GAPDH activity. malonyl-NAC increases GAPDH malonylation in cells and inhibits pyruvate kinase activity. In addition, malonyl-NAC limits the metabolism and proliferation of a highly glycolytic kidney cancer cell line harboring a tricarboxylic acid cycle mutation[1]. | [References]
[1] Kulkarni RA, et al. Discovering Targets of Non-enzymatic Acylation by Thioester Reactivity Profiling. Cell Chem Biol. 2017 Feb 16;24(2):231-242. DOI:10.1016/j.chembiol.2017.01.002 |
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