ChemicalBook--->CAS DataBase List--->2375541-73-2

2375541-73-2

Request For Quotation
2375541-73-2 Structure

2375541-73-2 Structure
IdentificationBack Directory
[Name]

Autogramin-1
[CAS]

2375541-73-2
[Synonyms]

Autogramin-1
Inhibitor,inhibit,Autogramin1,Autogramin-1,Autophagy,Autogramin 1
tert-butyl 2-(2,4-dioxo-3-propyl-1,2,3,4-tetrahydroquinazoline-7-carboxamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate
Thiazolo[5,4-c]pyridine-5(4H)-carboxylic acid, 6,7-dihydro-2-[[(1,2,3,4-tetrahydro-2,4-dioxo-3-propyl-7-quinazolinyl)carbonyl]amino]-, 1,1-dimethylethyl ester
[Molecular Formula]

C23H27N5O5S
[MOL File]

2375541-73-2.mol
[Molecular Weight]

485.56
Chemical PropertiesBack Directory
[density ]

1.359±0.06 g/cm3(Predicted)
[form ]

Solid
[pka]

6.67±0.20(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

Autogramin-1 potently inhibits autophagy induced by either starvation (IC50=0.17 μM) or mTORC1 inhibition (Rapamycin; IC50=0.44 μM)[1].
[References]

[1] Laraia L, et al. The cholesterol transfer protein GRAMD1A regulates autophagosome biogenesis. Nat Chem Biol. 2019 Jul;15(7):710-720. DOI:10.1038/s41589-019-0307-5
Spectrum DetailBack Directory
[Spectrum Detail]

Autogramin-1(2375541-73-2)1HNMR
2375541-73-2 suppliers list
Company Name: ChemShuttle, Inc.  
Telephone: 0510-83588313-811 18800520310
Website: www.jiehuapharma.com/
Company Name: Shanghai EFE Biological Technology Co., Ltd.  
Telephone: 021-65675885 18964387627
Website: http://www.efebio.com
Company Name: Shanghai Rechem science Co., Ltd.  
Telephone: 021-31433387 15618786686
Website: http://cn.rechemscience.com
Company Name: Chuzhou KeMail Chemical Technology Co., Ltd  
Telephone: 0550-5196001 15000891977
Website: https://www.chemicalbook.com/ShowSupplierProductsList19947/0_EN.htm
Company Name: Zhejiang J&C Biological Technology Co.,Limited  
Telephone: +1-2135480471
Website: https://www.sarms4muscle.com
Company Name: ShangHai ChuanQian Chemcial Technique Centre  
Telephone: 15869524721
Website: www.chemicalbook.com/ShowSupplierProductsList68594/0_EN.htm
Company Name: cjbscvictory  
Telephone: 13348960310 13348960310
Website: www.weikeqi-biotech.com/
Company Name: Wuhan Augda Biotechnology Co., Ltd  
Telephone: 15071299552
Website: https://www.chemicalbook.com/supplier/24275232/1.htm
Company Name: Bide Pharmatech Ltd.  
Telephone: 400-1647117 13681763483
Website: https://www.bidepharm.com/
Company Name: TargetMol Chemicals Inc.  
Telephone: 4008200310 15002144251
Website: https://www.targetmol.cn/
Company Name: Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd  
Telephone: 024-88590548 18698872706
Website:
Company Name: Wuhan Jingkangen Biomedical Technology Co., Ltd  
Telephone: 13720134139 086-15871494362 13720134139
Website: https://www.jknbiochem.com
Company Name: Nantong QuanYi Biotechnology Co., Ltd  
Telephone: 0513-66337626 18051384581
Website: https://www.chemhifuture.com/
Company Name: Zibo Hangyu Biotechnology Development Co., Ltd  
Telephone: 13053322091 13053322091
Website: www.chemicalbook.com/showsupplierproductslist1804467/0_en.htm
Company Name: Beijing Boorsen Biotechnology Co., Ltd  
Telephone: 400-901-9800 18611424007
Website: www.bioss.com.cn/
Company Name: ZhengZhou Edward Biology Co.,Ltd  
Telephone: 13298105281
Website: www.edwardbiology.cn
Company Name: Changsha Fuzhen Biotechnology Co.，LTD  
Telephone: 15111215862 18229892877
Website: www.fuzhenbiochem.com/
Company Name: Olix ( Hubei) Pharmaceutical Technology Co., Ltd  
Telephone: 17316404525 17316404525
Website: www.olix.cn
Tags:2375541-73-2 Related Product Information
2375541-73-2 2375541-45-8 25316-40-9 763113-22-0