| Identification | Back Directory | [Name]
(2S,4R)-1-((S)-1-amino-17-(tert-butyl)-15-oxo-3,6,9,12-tetraoxa-16-azaoctadecan-18-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride | [CAS]
2376139-48-7 | [Synonyms]
(2S,4R)-1-((S)-1-amino-17-(tert-butyl)-15-oxo-3,6,9,12-tetraoxa-16-azaoctadecan-18-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride | [Molecular Formula]
C33H51N5O8S.ClH | [MOL File]
2376139-48-7.mol | [Molecular Weight]
714.31 |
| Chemical Properties | Back Directory | [storage temp. ]
2-8°C | [form ]
crystals (or crystals with chunks) | [color ]
White to Light Yellow | [InChIKey]
XKGVWUPEGSRRJY-ABLBDAGXSA-N | [SMILES]
C([C@@H](NC(CCOCCOCCOCCOCCN)=O)[C@](C)(C)C)(=O)N1[C@H](C(NCC2=CC=C(C=C2)C3=C(C)N=CS3)=O)C[C@@H](O)C1.Cl |
| Hazard Information | Back Directory | [Uses]
(S,R,S)-AHPC-CO-PEG4-C2-amine HCl is a functionalized functionalized von Hippel-Lindau (VHL) ligand. It contains a terminal amine for conjugation with carboxylic acid linkers. A basic building block for development of a protein degrader library.
Technology Spotlight:
Degrader Building Blocks for Targeted Protein Degradation
Protein Degrader Building Blocks |
|
| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
|