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2376189-62-5

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2376189-62-5 Structure

2376189-62-5 Structure

Identification	Back Directory
[Name] Cyclopenta[c]pyrrole-5-carboxylic acid, 5-amino-4-[3-(dihydroxyborano)propyl]octahydro-, (3aR,4S,5S,6aR)-
[CAS] 2376189-62-5
[Synonyms] ARG1-IN-1 Cyclopenta[c]pyrrole-5-carboxylic acid, 5-amino-4-[3-(dihydroxyborano)propyl]octahydro-, (3aR,4S,5S,6aR)-
[Molecular Formula] C11H21BN2O4
[MOL File] 2376189-62-5.mol
[Molecular Weight] 256.11

Chemical Properties	Back Directory
[Boiling point ] 496.2±55.0 °C(Predicted)
[density ] 1.229±0.06 g/cm3(Predicted)
[pka] 2.26±0.40(Predicted)

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[Uses] ARG1-IN-1 (example 1) is a human arginase 1 inhibitor with an IC50 of 29 nM[1].
[References] [1] Mitcheltree MJ, et al. Discovery and Optimization of Rationally Designed Bicyclic Inhibitors of Human Arginase to Enhance Cancer Immunotherapy. ACS Med Chem Lett. 2020 Mar 23;11(4):582-588. DOI:10.1021/acsmedchemlett.0c00058

2376189-62-5 suppliers list

Company Name:	BOC Sciences
Tel:	16314854226; +8616314854226 , +8616314854226
Website:	https://www.bocsci.com/

Company Name:	TargetMol Chemicals Inc.
Tel:	15002134094
Website:	https://www.targetmol.cn/

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